Understanding Lab Tests for Hypogammaglobulinemia
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Hypogammaglobulinemia is a condition characterized by abnormally low levels of immunoglobulins (antibodies) in the blood. These proteins are essential components of the immune system that help fight infections. Specific blood tests are necessary to diagnose this condition and assess immune function.
Recommended Test
IgG
This test measures the level of Immunoglobulin G (IgG) in the blood, which is the most abundant type of antibody in the bloodstream. Low IgG levels are a key indicator of hypogammaglobulinemia, a condition that significantly increases susceptibility to bacterial and viral infections due to compromised immune function.
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Diagnosing Hypogammaglobulinemia
Since hypogammaglobulinemia often presents with recurrent infections or may be asymptomatic, blood testing is the primary method for diagnosis. Measuring specific immunoglobulin levels helps healthcare providers determine if the immune system is functioning properly and identify patients at higher risk for infections.
Understanding Your Results
IgG levels below the normal range may indicate hypogammaglobulinemia, which can be either primary (genetic) or secondary (caused by other conditions or medications). Your healthcare provider will interpret results in the context of your medical history, symptoms, and may recommend additional immunoglobulin tests (IgA, IgM) for a complete assessment.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.
