Understanding Lab Tests for HTLV-I-associated uveitis

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

HTLV-I-associated uveitis is a rare inflammatory eye disease caused by infection with the Human T-Cell Lymphotropic Virus Type I (HTLV-I). This condition affects the uvea, the middle layer of the eye, and can lead to vision problems if left untreated. Blood testing is essential for confirming the underlying viral infection.

Recommended Test

Human T-Cell Lymphotropic Virus I, II (HTLV-I/HTLV-II) Antibodies, Preliminary Test W/ Confirmation

This comprehensive blood test detects antibodies against HTLV-I and HTLV-II viruses. The presence of HTLV-I antibodies confirms infection with the virus that causes HTLV-I-associated uveitis. The test includes both preliminary screening and confirmatory testing to ensure accurate results and proper diagnosis of this rare inflammatory eye condition.

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Diagnosing HTLV-I-associated Uveitis

While eye examination reveals the inflammatory changes characteristic of uveitis, confirming HTLV-I as the underlying cause requires specific blood testing. This viral infection can remain dormant for years before causing complications like uveitis, making laboratory confirmation crucial for proper diagnosis and treatment.

Understanding the Test Results

A positive HTLV-I antibody test indicates current or past infection with the virus. In patients presenting with uveitis symptoms, this positive result helps establish the diagnosis of HTLV-I-associated uveitis and guides appropriate treatment strategies to manage both the viral infection and the inflammatory eye condition.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.

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