Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Hormone-sensitive cancers are cancers that depend on hormones like estrogen, progesterone, or testosterone for their growth. These include breast cancer, prostate cancer, endometrial cancer, and ovarian cancer. While blood tests cannot directly diagnose these cancers, they play a crucial role in assessing hormone levels and related factors that may influence cancer risk and management.
SHBG is a protein that binds to sex hormones like testosterone and estrogen, regulating their availability in the body. Abnormal SHBG levels may indicate altered hormone metabolism and have been associated with increased risk of hormone-sensitive cancers, particularly breast and prostate cancer. This test helps assess the hormonal environment that could influence cancer risk.
There is no single blood test that can diagnose hormone-sensitive cancers. Definitive diagnosis typically requires imaging studies and tissue biopsy. However, blood tests are fundamental for evaluating hormone levels, assessing risk factors, and monitoring the body's hormonal environment that may influence cancer development or progression.
Hormones play a significant role in the development and progression of certain cancers. By monitoring hormone-related markers like SHBG, healthcare providers can better understand an individual's hormonal profile and potential risk factors. This information can be valuable for developing prevention strategies and making informed healthcare decisions.
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment. Cancer screening and diagnosis require comprehensive evaluation including physical examination, imaging studies, and tissue analysis when appropriate.