Sample results
HIV progression is the rate at which HIV infection advances to AIDS and develops life-threatening complications. It is influenced by genetic factors, particularly Human Leukocyte Antigen (HLA) variants that regulate immune response to the virus. The HLA-A, B, C, DRB1 and DQ High Resolution test is the most important genetic test for assessing HIV progression risk.
HIV progression is caused by the human immunodeficiency virus gradually destroying CD4+ T cells, which are critical for immune system function. The virus replicates inside these cells, weakening your body's ability to fight infections and diseases. Genetic factors, particularly your HLA gene variants, significantly influence how quickly the virus damages your immune system, which is why some people progress to AIDS faster than others.
The HLA-A, B, C, DRB1 and DQ High Resolution test is the most important genetic test for assessing HIV progression risk because it identifies specific HLA gene variants that control how your immune system responds to HIV infection. Certain HLA-C alleles are scientifically associated with slower progression to AIDS, while other variants may indicate faster disease advancement. This comprehensive genetic analysis provides personalized information about your inherited predisposition to disease progression rates, helping your healthcare team develop targeted monitoring and treatment strategies based on your unique genetic profile.
You should get tested if you have recently been diagnosed with HIV and want to understand your genetic risk factors for disease progression. Testing is particularly valuable when planning long-term treatment strategies with your healthcare provider, or if you want personalized information about how your immune system genetics may influence disease advancement. Early genetic testing helps establish a baseline understanding of your progression risk, allowing for more informed decisions about monitoring frequency and treatment approaches.
What this means
Your HLA typing results show a compatible match with the potential donor, meaning your immune system markers align well enough to proceed with transplant evaluation. This increases the likelihood of transplant success and reduces the risk of acute rejection.
Recommended actions
Share these results with your transplant coordinator immediately to move forward
Continue with additional crossmatch testing and medical evaluations as directed
Discuss immunosuppression protocols and post-transplant care with your medical team
Maintain overall health through balanced nutrition and following pre-transplant guidelines
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Sample results
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