Understanding Lab Tests for High Thiamine Levels

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

Thiamine, also known as vitamin B1, is a water-soluble vitamin essential for energy metabolism and nervous system function. While thiamine deficiency is more commonly discussed, elevated thiamine levels can occur due to excessive supplementation or certain medical conditions.

Recommended Test

Vitamin B1 (Thiamine) LC/MS/MS

This advanced liquid chromatography-tandem mass spectrometry test provides precise measurement of thiamine levels in the blood. It can detect elevated levels that may result from excessive intake, helping to identify potential causes of side effects such as skin rashes, stomach upset, or kidney stones that can sometimes occur with very high doses.

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Why Test for High Thiamine Levels

Although thiamine is generally considered safe because excess amounts are typically excreted in urine, very high levels from excessive supplementation can occasionally cause side effects. Blood testing is fundamental for accurately measuring thiamine levels to assess whether intake is appropriate or potentially excessive.

Understanding High Thiamine Levels

Since thiamine is water-soluble, the body typically eliminates excess amounts through urine, making toxicity rare. However, monitoring levels through blood testing helps ensure that supplementation is appropriate and not causing unwanted effects. This is particularly important for individuals taking high-dose supplements or receiving thiamine injections.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.

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