Understanding Lab Tests for Herpetic Whitlow
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Herpetic whitlow is a painful viral infection that affects the fingers and thumbs, typically caused by herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2). This condition is commonly seen in healthcare workers, children who suck their thumbs, and individuals with oral or genital herpes. While the diagnosis is often made through clinical examination of the characteristic painful blisters, blood tests can help confirm the presence of HSV infection.
Recommended Test
Herpes Simplex Virus 1 and 2 (IgG), with Reflex to HSV-2 Inhibition
This comprehensive test detects IgG antibodies against both HSV-1 and HSV-2, helping to identify which strain of the herpes simplex virus is causing the herpetic whitlow infection. The reflex to HSV-2 inhibition provides additional specificity for HSV-2 detection, which is important since both viral types can cause this painful finger infection.
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The Role of Blood Testing in Herpetic Whitlow
Blood tests for herpetic whitlow primarily detect antibodies (IgG) that the immune system produces in response to HSV infection. These tests are valuable for confirming exposure to the herpes simplex virus and can help differentiate between HSV-1 and HSV-2 as the causative agent, which may influence treatment decisions and patient counseling.
Understanding Your Results
A positive IgG result indicates past or current infection with HSV-1 or HSV-2. Since herpetic whitlow can be caused by either virus type, identifying the specific strain helps healthcare providers understand the likely source of infection and provide appropriate patient education about transmission risks and recurrence patterns.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment of suspected herpetic whitlow or any finger infection.
