Understanding Lab Tests for Herpetic Keratitis
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Herpetic keratitis is a serious eye infection caused by the herpes simplex virus (HSV) that affects the cornea. While the condition is primarily diagnosed through comprehensive eye examination by an ophthalmologist, blood testing plays a crucial supporting role in confirming the underlying viral infection and guiding appropriate treatment decisions.
Recommended Test
Herpes Simplex Virus 1 and 2 (IgG), with Reflex to HSV-2 Inhibition
This comprehensive test detects IgG antibodies against both HSV-1 and HSV-2, which can cause herpetic keratitis. Elevated levels of HSV-1 IgG antibodies may indicate a past or present infection, helping to confirm the viral cause of the eye condition. The test includes reflex testing to HSV-2 inhibition for accurate differentiation between the two virus types, which is important for understanding the specific strain involved in the infection.
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Why Blood Testing is Important for Herpetic Keratitis
Although there isn't a single blood test to diagnose herpetic keratitis itself, testing for herpes simplex virus antibodies is fundamental for confirming exposure to the virus and understanding the body's immune response. This information helps healthcare providers differentiate herpetic keratitis from other eye conditions and develop the most effective treatment plan.
Understanding the Connection
Herpetic keratitis is a potentially sight-threatening condition that can lead to corneal scarring and blindness if not properly managed. By confirming HSV infection through blood testing, healthcare providers can better understand the patient's viral status and implement appropriate antiviral therapy to prevent recurrent episodes and protect vision.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment of eye conditions.
