Understanding Lab Tests for Hepatitis D Infection
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Hepatitis D, also known as Delta Hepatitis, is a serious liver infection caused by the Hepatitis D virus (HDV). This unique virus can only infect individuals who are already infected with Hepatitis B, as it requires the Hepatitis B virus to replicate. Blood tests are essential for diagnosing this potentially severe co-infection.
Recommended Test
Hep B Core Antibody, IgM
This test detects IgM antibodies against the Hepatitis B core antigen, which indicates recent or acute Hepatitis B infection. Since Hepatitis D can only occur in individuals with Hepatitis B infection, the presence of Hepatitis B Core Antibody (IgM) can help identify co-infection or superinfection patterns with Hepatitis D, providing critical information for diagnosis and treatment planning.
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The Relationship Between Hepatitis B and Hepatitis D
Hepatitis D infection occurs in two forms: co-infection (simultaneous infection with both Hepatitis B and D) or superinfection (Hepatitis D infection in someone already chronically infected with Hepatitis B). Because of this dependency, testing for Hepatitis B markers is crucial in diagnosing and understanding Hepatitis D infection patterns.
Why Early Detection Matters
Hepatitis D infection can lead to more severe liver disease than Hepatitis B alone, including rapid progression to cirrhosis and liver failure. Early detection through appropriate blood testing allows healthcare providers to implement proper monitoring and treatment strategies to prevent serious complications.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment of hepatitis infections.
