Understanding Lab Tests for Hepatitis D Co-infection

Hepatitis D co-infection is a unique condition where the Hepatitis D virus (HDV) infects a person simultaneously with or after Hepatitis B virus (HBV). HDV is a defective virus that can only replicate in the presence of HBV, making co-infection diagnosis complex and requiring specific blood testing strategies.

Recommended Test

Why Blood Testing is Essential for Hepatitis D Co-infection

Since Hepatitis D cannot exist without Hepatitis B, diagnosing a co-infection requires testing for both viruses. Blood tests are fundamental for detecting active Hepatitis B infection, which may indicate the possibility of Hepatitis D co-infection, and for monitoring the body's immune response to these viral infections.

Understanding the Co-infection Process

Hepatitis D co-infection typically occurs in two ways: simultaneous infection with both viruses or superinfection where HDV infects someone already carrying HBV. The Hep B Core Antibody IgM test helps identify active Hepatitis B infection, which is a prerequisite for any Hepatitis D infection to occur.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment. Additional specialized testing for Hepatitis D antibodies and RNA may be necessary to confirm co-infection.

References

• https://www.cdc.gov/hepatitis/hdv/index.htm
• https://www.niddk.nih.gov/health-information/liver-disease/viral-hepatitis/hepatitis-b
• https://medlineplus.gov/hepatitisb.html