Understanding Lab Tests for Hairy Cell Leukemia
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Hairy cell leukemia is a rare type of blood cancer that affects B-lymphocytes, a type of white blood cell. This slow-growing cancer gets its name from the hair-like projections that appear on the affected cells when viewed under a microscope. While the initial diagnosis typically involves blood cell analysis and bone marrow examination, specialized genetic testing plays a crucial role in confirming the diagnosis.
Recommended Test
BRAF Mutation Analysis
This genetic test identifies BRAF mutations, which are present in almost all cases of hairy cell leukemia. The detection of this specific genetic change helps confirm the diagnosis and can guide healthcare providers in selecting the most appropriate treatment approach for this rare blood cancer.
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The Role of Genetic Testing in Hairy Cell Leukemia
Hairy cell leukemia has a distinctive genetic signature that can be detected through blood testing. A specific genetic mutation is found in nearly all patients with this condition, making genetic analysis a powerful tool for both diagnosis confirmation and treatment planning.
Understanding BRAF Mutation Testing
The BRAF gene normally helps control cell growth and division. When this gene is mutated in hairy cell leukemia, it contributes to the abnormal growth of B-lymphocytes. Testing for this mutation provides valuable diagnostic information and may influence treatment decisions, as targeted therapies are available for BRAF-positive cancers.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Hairy cell leukemia diagnosis and treatment require specialized hematologic care. Always consult with a healthcare provider or hematologist for proper diagnosis and treatment planning.
