H. Pylori infection is a bacterial infection of the stomach lining that causes peptic ulcers and chronic gastritis. It is caused by Helicobacter pylori, a spiral-shaped bacteria that colonizes the stomach and weakens its protective mucous layer. The H. Pylori Antigen Stool test is the most important test for diagnosis because it directly detects active bacterial infection.
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H. Pylori infection is caused by Helicobacter pylori bacteria that enter your body through contaminated food, water, or direct contact with an infected person's saliva or other body fluids. Once inside, the bacteria burrow into the protective mucous lining of your stomach, where they release enzymes that neutralize stomach acid and allow them to survive. This bacterial colonization triggers an immune response that causes inflammation, gradually damaging the stomach lining and creating conditions that lead to ulcers and gastritis. The infection is typically acquired during childhood and can persist for decades if left untreated.
The H. Pylori Antigen Stool test is the most important test for H. Pylori infection because it directly detects bacterial proteins in your stool, providing definitive proof of an active, current infection. Unlike antibody blood tests that only show past exposure, the stool antigen test confirms that H. pylori bacteria are currently living in your stomach and actively causing inflammation. This non-invasive test is highly accurate with sensitivity rates above 95%, making it the preferred diagnostic method recommended by gastroenterologists. The test is particularly valuable for both initial diagnosis and for confirming successful eradication after antibiotic treatment.
You should get tested if you experience persistent stomach pain or burning sensations, especially between meals or at night, unexplained nausea or vomiting, frequent bloating or feeling full after eating small amounts, or black tarry stools that could indicate bleeding ulcers. Testing is also important if you have a family history of stomach ulcers or stomach cancer, have been taking long-term anti-inflammatory medications like ibuprofen, or have been diagnosed with iron-deficiency anemia without an obvious cause. Early detection allows for prompt antibiotic treatment that can cure the infection and prevent serious complications like peptic ulcers and stomach cancer.
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What this means
Your test came back negative, meaning no H. Pylori bacteria was detected in your stool sample. This is a healthy result that rules out H. Pylori as the cause of your digestive symptoms. If you continue experiencing stomach issues, other causes such as diet, stress, or other gastrointestinal conditions may need to be explored.
Recommended actions
Maintain a balanced diet with plenty of fiber and avoid trigger foods like spicy or acidic items
Manage stress through relaxation techniques as it can affect digestion
Keep a food diary to identify any patterns with digestive discomfort
If symptoms persist, consult with a gastroenterologist to explore other possible causes
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