Understanding Lab Tests for Fibromyalgia
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Fibromyalgia is a chronic condition characterized by widespread musculoskeletal pain, fatigue, and tender points throughout the body. There is no single blood test that can diagnose fibromyalgia, as the condition is typically diagnosed through clinical evaluation and symptom assessment. However, lab testing plays an important role in understanding underlying biochemical factors that may contribute to symptoms.
Recommended Test
Serotonin, Serum
This test measures serotonin levels in the blood. Low serotonin levels have been associated with fibromyalgia, as this neurotransmitter plays a crucial role in pain regulation and mood. Decreased serotonin may heighten the body's sensitivity to pain, contributing to the widespread discomfort characteristic of fibromyalgia.
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Why Blood Testing is Important in Fibromyalgia
While fibromyalgia diagnosis relies on clinical criteria, blood tests are fundamental for assessing neurotransmitter levels and other biomarkers that may influence pain sensitivity and symptom severity. Testing can help healthcare providers better understand the underlying mechanisms contributing to your symptoms and guide treatment approaches.
Understanding Your Results
Serotonin testing can provide valuable insights into one of the potential biochemical factors underlying fibromyalgia symptoms. Low levels may help explain increased pain sensitivity and can guide treatment decisions, including the consideration of medications that affect serotonin levels or lifestyle interventions that support natural serotonin production.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment of fibromyalgia.
