Understanding Lab Tests for Factor VII Deficiency
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Factor VII deficiency is a rare inherited bleeding disorder caused by low levels or absence of Factor VII, a crucial protein in the blood clotting process. This condition can lead to prolonged bleeding after injury or surgery, and requires specific blood tests for accurate diagnosis.
Recommended Test
Prothrombin Time (PT) (INR)
This test measures how long it takes for blood to clot and is directly affected by Factor VII levels. Since Factor VII is essential for the extrinsic pathway of coagulation, a deficiency in this protein will cause a prolonged PT/INR result, making this test a primary screening tool for Factor VII deficiency.
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Diagnosing Factor VII Deficiency
Since Factor VII deficiency symptoms can vary widely and may be mistaken for other bleeding disorders, laboratory testing is essential for a definitive diagnosis. Blood tests that measure clotting function can detect abnormalities in the coagulation pathway where Factor VII plays a critical role.
Understanding Your Results
A prolonged PT/INR may indicate Factor VII deficiency, but additional specialized coagulation studies are typically needed to confirm the diagnosis and determine the severity. Your healthcare provider will interpret these results in the context of your symptoms and medical history.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.
