Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Factitious hypoglycemia is a condition where dangerously low blood sugar levels are caused by the intentional or accidental intake of insulin or other antidiabetic medications. Unlike naturally occurring hypoglycemia, this condition requires specific laboratory testing to identify the external source of blood sugar lowering.
This test measures C-peptide levels in the blood, which is produced naturally when the pancreas makes insulin. In factitious hypoglycemia caused by external insulin or antidiabetic drug intake, C-peptide levels will be abnormally low because the body's natural insulin production is suppressed. This helps distinguish medication-induced hypoglycemia from other causes where C-peptide levels would be normal or elevated.
While basic blood glucose tests can confirm low blood sugar, they cannot distinguish between natural causes and medication-induced hypoglycemia. Specialized blood tests are crucial for identifying the underlying cause and ensuring appropriate treatment, as the management differs significantly from other forms of hypoglycemia.
Low C-peptide levels during an episode of hypoglycemia strongly suggest factitious hypoglycemia, indicating that the low blood sugar is due to external sources rather than the body's natural processes. This information is vital for healthcare providers to determine the appropriate treatment approach and address any underlying issues.
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.