Understanding Lab Tests for Factitious Hypoglycemia

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

Factitious hypoglycemia is a condition where dangerously low blood sugar levels are caused by the intentional or accidental intake of insulin or other antidiabetic medications. Unlike naturally occurring hypoglycemia, this condition requires specific laboratory testing to identify the external source of blood sugar lowering.

Recommended Test

C-Peptide, Serum

This test measures C-peptide levels in the blood, which is produced naturally when the pancreas makes insulin. In factitious hypoglycemia caused by external insulin or antidiabetic drug intake, C-peptide levels will be abnormally low because the body's natural insulin production is suppressed. This helps distinguish medication-induced hypoglycemia from other causes where C-peptide levels would be normal or elevated.

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Why Specialized Testing is Essential

While basic blood glucose tests can confirm low blood sugar, they cannot distinguish between natural causes and medication-induced hypoglycemia. Specialized blood tests are crucial for identifying the underlying cause and ensuring appropriate treatment, as the management differs significantly from other forms of hypoglycemia.

Understanding the Results

Low C-peptide levels during an episode of hypoglycemia strongly suggest factitious hypoglycemia, indicating that the low blood sugar is due to external sources rather than the body's natural processes. This information is vital for healthcare providers to determine the appropriate treatment approach and address any underlying issues.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.

References