Understanding Lab Tests for Estrogen-sensitive cancers

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

Estrogen-sensitive cancers, including certain types of breast, endometrial, and ovarian cancers, are diagnosed through tissue biopsy and imaging studies. While there is no blood test to diagnose these cancers directly, hormone level testing plays a crucial role in monitoring estrogen levels that may influence cancer development and progression.

Recommended Test

Estrone, LC/MS/MS

This highly sensitive test measures estrone levels in the blood using advanced LC/MS/MS technology. Elevated estrone levels can promote the growth of estrogen-sensitive cancers, such as breast and uterine cancer. Monitoring these levels is important for assessing hormonal influence on cancer risk and treatment response.

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Why Hormone Testing is Important

Estrogen-sensitive cancers have receptors that respond to estrogen hormones, which can stimulate tumor growth. Blood testing is fundamental for assessing hormone levels, monitoring treatment effectiveness, and evaluating risk factors that may contribute to cancer development or recurrence.

Clinical Significance

Estrone is one of the three main estrogen hormones and can be particularly elevated in postmenopausal women due to conversion from other hormones in fat tissue. Understanding estrone levels can help healthcare providers make informed decisions about hormone therapy, cancer prevention strategies, and treatment monitoring.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment. Cancer diagnosis requires appropriate imaging studies and tissue biopsy confirmation.

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