Question 1

What is Estrogen-sensitive cancers?

Accepted Answer

Estrogen-sensitive cancers are malignancies that have receptors responding to estrogen hormones, including certain breast, endometrial, and ovarian cancers. These cancers are fueled by estrogen hormones, particularly estrone, which binds to tumor receptors and stimulates cancer cell growth. The Estrone LC/MS/MS test is the most important test for monitoring hormone levels that influence estrogen-sensitive cancer development and treatment response.

Question 2

What causes estrogen-sensitive cancers?

Accepted Answer

Estrogen-sensitive cancers are caused by abnormal cells that develop estrogen receptors, which respond to estrogen hormones and trigger uncontrolled cell growth. Estrone, estradiol, and estriol are the three main estrogen hormones that can bind to these receptors and stimulate tumor development. In postmenopausal women, estrone becomes particularly important because fat tissue converts other hormones into estrone, creating a constant source of cancer-fueling estrogen even after menopause.

Question 3

What is the best test for estrogen-sensitive cancers?

Accepted Answer

The Estrone LC/MS/MS test is the most important blood test for monitoring estrogen-sensitive cancers because it measures estrone levels with exceptional precision using liquid chromatography-mass spectrometry technology. Estrone is the primary estrogen in postmenopausal women and can be converted to estradiol in tumor tissue, directly fueling cancer growth. While cancer diagnosis requires tissue biopsy and imaging studies, this test is essential for assessing hormonal influence on cancer risk, monitoring treatment effectiveness, and making decisions about hormone therapy strategies.

Question 4

When should I get tested for estrogen-sensitive cancers?

Accepted Answer

You should get tested if you have been diagnosed with breast, uterine, or ovarian cancer and need to monitor hormone levels during treatment. Testing is also important if you are considering hormone replacement therapy and have a family history of estrogen-sensitive cancers, or if you are postmenopausal with elevated cancer risk factors like obesity or late menopause. Regular monitoring helps your healthcare provider make informed decisions about cancer prevention strategies and treatment adjustments.

Question 5

What are the symptoms of estrogen-sensitive cancers?

Accepted Answer

Symptoms vary depending on cancer type but may include a breast lump or thickening, abnormal vaginal bleeding especially after menopause, unusual vaginal discharge, pelvic pain or pressure, and changes in breast size or shape. Some women notice persistent bloating, unexplained weight loss, or changes in bowel or bladder habits. Early-stage estrogen-sensitive cancers often have no symptoms, which is why regular screening mammograms and pelvic exams are crucial for early detection.

Question 6

Who is at risk for estrogen-sensitive cancers?

Accepted Answer

Women with prolonged estrogen exposure face higher risk, including those who started menstruating early, experienced late menopause, never had children, or had their first child after age 30. Additional risk factors include obesity (fat tissue produces estrogen), long-term hormone replacement therapy use, family history of breast or ovarian cancer, BRCA1 or BRCA2 genetic mutations, and dense breast tissue. Postmenopausal women with elevated estrone levels from excess body fat are at particularly high risk.

Question 7

What happens if estrogen-sensitive cancers are left untreated?

Accepted Answer

Untreated estrogen-sensitive cancers continue growing and spreading to nearby tissues and distant organs through the bloodstream and lymphatic system. Breast cancer can metastasize to bones, liver, lungs, and brain, while endometrial cancer can spread through the pelvis and abdomen. Ovarian cancer often spreads silently throughout the abdominal cavity before causing symptoms. Without treatment, these cancers eventually become life-threatening, causing organ failure, severe pain, and significantly reduced survival rates.

Question 8

Can estrogen-sensitive cancers be diagnosed with a blood test?

Accepted Answer

Blood tests cannot diagnose estrogen-sensitive cancers directly, but they play a crucial supporting role in cancer management. Cancer diagnosis requires tissue biopsy to examine cells under a microscope and imaging studies like mammography, ultrasound, or MRI to visualize tumors. However, the Estrone LC/MS/MS blood test measures hormone levels that influence cancer growth and helps doctors monitor treatment effectiveness, assess recurrence risk, and make decisions about hormone-blocking therapies.

Question 9

How are estrogen-sensitive cancers treated?

Accepted Answer

Treatment typically combines surgery to remove tumors, radiation therapy to kill remaining cancer cells, and systemic therapies like chemotherapy. Hormone-blocking medications are especially important for estrogen-sensitive cancers, including tamoxifen (which blocks estrogen receptors) and aromatase inhibitors (which reduce estrogen production). Many women receive combination therapy tailored to their cancer stage, hormone receptor status, and overall health. Regular monitoring of estrone levels helps doctors adjust hormone therapy for maximum effectiveness.

Question 10

How can I prevent estrogen-sensitive cancers?

Accepted Answer

Maintaining a healthy weight significantly reduces risk because excess body fat produces estrogen. Regular exercise, limiting alcohol consumption to no more than one drink per day, and avoiding long-term hormone replacement therapy also help lower risk. Women with strong family histories may consider genetic counseling and testing for BRCA mutations, with preventive options including more frequent screening, chemoprevention medications like tamoxifen, or risk-reducing surgeries. Breastfeeding for at least one year provides protective benefits by reducing lifetime estrogen exposure.

Question 11

What natural approaches support estrogen-sensitive cancer prevention?

Accepted Answer

Eating a diet rich in cruciferous vegetables like broccoli, cauliflower, and Brussels sprouts supports healthy estrogen metabolism through compounds called indole-3-carbinol. Regular physical activity helps maintain healthy weight and reduces estrogen production in fat tissue. Limiting processed foods, reducing alcohol intake, and consuming fiber-rich foods help the body eliminate excess estrogen through regular bowel movements. While these lifestyle approaches support overall health and may reduce cancer risk, they should complement rather than replace medical screening and professional healthcare guidance.

Question 12

How’s this work?

Accepted Answer

Getting your blood test with us is easy, private & backed by the power of science.Long story short:
            
                In the test options, use the filters or search box to narrow your choices and find the test you want.
                If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
                Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
                If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
                When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
                Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
                You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
                If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Question 13

How do I know which test to get?

Accepted Answer

In the test options, find the test you want.
            If you’re not sure which test to get, we can lend a hand in finding the right option.
            Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

Question 14

When will my lab results be available?

Accepted Answer

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know.
            After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop!
            If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Question 15

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Accepted Answer

Absolutely! We totally understand that errors can happen. No worries, we're here to help you.
            Just reach out to us via text at 754-799-7833 or shoot us an email at
            support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update.
            Our awesome team will jump right in and make sure everything is sorted out and accurate for you.
            There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.
            Our lab requires an address to be listed to generate an order.

Question 16

Do you accept health insurance?

Accepted Answer

Only HSA & FSA is accepted.
            Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.
            This policy applies to all insurance companies, including federal health insurance programs like Medicare.
            If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Question 17

Can I cancel my order?

Accepted Answer

Yes.
            We get it – sometimes your needs change.
            As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.
            If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com.
            You can read more about our cancellation policy here.

Question 18

How can I find a lab location near me?

Accepted Answer

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached!
            You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).
            Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.
            If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Estrogen-Sensitive Cancer Blood Test

What is Estrogen-sensitive cancers?

What causes estrogen-sensitive cancers?

What is the best test for estrogen-sensitive cancers?

When should I get tested for estrogen-sensitive cancers?

References

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