Understanding Lab Tests for Endometriosis
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Endometriosis is a condition where tissue similar to the uterine lining grows outside the uterus, causing pain and other symptoms. While endometriosis is typically diagnosed through imaging and surgical procedures, blood tests play an important supporting role in monitoring the condition and assessing hormonal factors that may influence its progression.
Top Recommended Test
Estrogens (Total), Serum
This test measures total estrogen levels in the blood. Endometriosis is often associated with high levels of estrogen, which can stimulate the growth of endometrial tissue outside the uterus. Monitoring estrogen levels helps assess hormonal influences on the condition and guide treatment decisions.
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The Role of Blood Testing in Endometriosis
There isn't a single blood test that can definitively diagnose endometriosis. However, blood testing is fundamental for monitoring hormone levels that may fuel the condition, checking for elevated markers associated with endometrial tissue growth, and assessing the body's response to treatment.
Other Relevant Tests
CA-125 (Ovarian Cancer Test)
While primarily used as a cancer marker, CA-125 can sometimes be elevated in endometriosis cases. This protein marker may be raised when endometrial-like tissue grows in other parts of the body, making it a useful tool for monitoring disease activity and treatment response.
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Understanding Your Results
Elevated estrogen levels may indicate hormonal imbalances that could worsen endometriosis symptoms. An elevated CA-125 level, while not diagnostic on its own, may suggest active endometrial tissue growth. These tests should always be interpreted alongside clinical symptoms and other diagnostic findings by a healthcare provider.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment of endometriosis.
