Understanding Lab Tests for Endometrial Cancer

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

Endometrial cancer is a type of cancer that begins in the lining of the uterus (endometrium). While endometrial cancer is typically diagnosed through tissue biopsy and imaging studies, blood testing plays a crucial role in assessing hormonal factors that can influence cancer risk and monitoring overall health during treatment.

Top Recommended Test

Estrogens (Total), Serum

This test measures total estrogen levels in the blood. Elevated estrogen levels relative to progesterone can stimulate excessive growth of the endometrial lining, which increases the risk of developing endometrial cancer. Monitoring estrogen levels helps assess hormonal risk factors.

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The Role of Hormones in Endometrial Cancer

Hormonal imbalances, particularly involving estrogen and progesterone, are significant risk factors for endometrial cancer development. Testing hormone levels is fundamental for understanding individual risk factors and can provide valuable information for prevention strategies and treatment planning.

Other Relevant Tests

Progesterone

This test measures progesterone levels, a hormone that helps regulate and balance the growth of the uterine lining. Low progesterone levels can lead to unopposed estrogen effects, potentially causing endometrial overgrowth and increasing cancer risk. Testing progesterone levels is essential for evaluating hormonal balance.

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Understanding Your Results

Hormone level testing provides valuable information about risk factors but does not diagnose endometrial cancer itself. Abnormal hormone levels may indicate increased risk and warrant further evaluation by a healthcare provider, including additional testing and preventive measures.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for proper diagnosis, risk assessment, and treatment of endometrial cancer concerns.

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