Understanding Lab Tests for Cow's Milk Protein Intolerance (CMPI)
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Cow's Milk Protein Intolerance (CMPI) is a condition where the immune system reacts to proteins found in cow's milk, causing digestive symptoms and discomfort. CMPI is typically diagnosed through clinical evaluation and dietary elimination trials rather than a single definitive blood test.
Recommended Test
Whey (f236) IgG
This test measures IgG antibodies specific to whey, one of the main proteins found in cow's milk. Elevated levels of Whey IgG antibodies could indicate an immune response to this milk protein, suggesting a potential intolerance. This information helps healthcare providers assess whether the immune system is reacting to cow's milk proteins and supports clinical decision-making regarding dietary modifications.
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Why Blood Testing is Important for CMPI
While there isn't a single blood test to directly diagnose CMPI, testing is fundamental for assessing the body's immune response to specific milk proteins. Blood tests can help healthcare providers understand whether the immune system is producing antibodies against cow's milk proteins, providing valuable supporting evidence for the condition.
Understanding the Results
It's important to note that elevated IgG levels to milk proteins should be interpreted alongside clinical symptoms and dietary history. The presence of antibodies doesn't automatically confirm CMPI, but it provides valuable information about immune system activity that can guide treatment decisions and dietary planning.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.
