Understanding Lab Tests for Congenital Fibrinogen Deficiency
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Congenital fibrinogen deficiency is a rare inherited bleeding disorder caused by genetic mutations that affect the production or function of fibrinogen, a crucial protein involved in blood clotting. This condition requires specialized blood testing for accurate diagnosis and management.
Recommended Test
Fibrinogen Activity
This test uses the Clauss method to measure functional fibrinogen levels in the blood. Low fibrinogen activity results are a direct indicator of congenital fibrinogen deficiency, making this the primary diagnostic test for confirming this rare genetic bleeding disorder.
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Diagnosing Congenital Fibrinogen Deficiency
Because the symptoms of fibrinogen deficiency, such as prolonged bleeding and easy bruising, can overlap with other bleeding disorders, specific laboratory testing is essential for a definitive diagnosis. Blood tests that measure fibrinogen levels and function are the primary diagnostic tools for this genetic condition.
Understanding Your Results
Normal fibrinogen levels typically range from 200-400 mg/dL. In congenital fibrinogen deficiency, levels may be significantly reduced or completely absent, depending on the specific type and severity of the genetic mutation. Your healthcare provider will interpret these results in the context of your symptoms and medical history.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment. If you have a family history of bleeding disorders or experience unexplained bleeding episodes, genetic counseling may also be recommended.
