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Congenital CMV is a viral infection that occurs when a pregnant mother transmits the cytomegalovirus to her developing fetus during pregnancy. It is caused by primary or reactivated cytomegalovirus infection in the mother, which can cross the placenta and infect the baby. The Cytomegalovirus (CMV) Antibodies, IgG test is the most important test for assessing maternal CMV status and transmission risk to the fetus.
Congenital CMV is caused by cytomegalovirus infection in the mother during pregnancy that crosses the placenta to infect the developing fetus. The virus can be transmitted during a primary CMV infection when the mother is first exposed to the virus during pregnancy, or during reactivation of a previous CMV infection. Women who work with young children, have multiple sexual partners, or have weakened immune systems face higher risk of acquiring CMV during pregnancy and transmitting it to their baby.
The Cytomegalovirus (CMV) Antibodies, IgG test is the most important test for assessing congenital CMV risk because it measures IgG antibodies in the mother's blood to determine her CMV infection status. High levels of CMV IgG antibodies indicate past or current exposure to the virus, and when combined with clinical assessment, help determine the risk of viral transmission to the fetus. This test is essential for pregnant women or those planning pregnancy because it identifies whether they have immunity to CMV or are at risk for primary infection during pregnancy, which poses the greatest danger to the developing baby.
You should get tested if you are pregnant or planning to become pregnant, especially if you work with young children in daycare or healthcare settings. Testing is particularly important if you develop flu-like symptoms, swollen glands, or fatigue during pregnancy, as these may indicate a primary CMV infection. Women with weakened immune systems or those who have had previous pregnancies affected by CMV should also get tested early in pregnancy to assess their risk and enable appropriate monitoring throughout the pregnancy.
What this means
Your test came back negative, meaning no CMV IgG antibodies were detected in your blood. This indicates you've never been infected with Cytomegalovirus and do not have immunity to it. If you're pregnant or planning pregnancy, your doctor may recommend precautions to avoid exposure.
Recommended actions
Practice thorough handwashing, especially after contact with young children's saliva or urine
Avoid sharing food, drinks, or utensils with young children
Discuss precautions with your doctor if you're pregnant or immunocompromised
Consider retesting each trimester if pregnant to monitor for new infection
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