Understanding Lab Tests for Colorectal Cancer

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

Colorectal cancer is typically diagnosed through colonoscopy, imaging studies, and tissue biopsy. While there isn't a single blood test to diagnose colorectal cancer itself, specialized laboratory testing plays a crucial role in cancer management, treatment planning, and monitoring the body's response to therapy.

Top Recommended Test

BRAF Mutation Analysis

This genetic test identifies BRAF mutations, which occur in approximately 10% of colorectal cancers. Testing for BRAF mutations is essential for treatment planning, as these mutations are associated with a poorer prognosis and resistance to certain types of chemotherapy. This information helps oncologists select the most effective treatment approach.

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The Role of Blood Testing in Colorectal Cancer

Blood tests for colorectal cancer serve multiple important purposes: they can help determine treatment options by identifying specific genetic mutations, monitor tumor markers that may indicate disease progression or response to treatment, and assess overall health status during cancer care.

Other Relevant Tests

IGF-2

This test measures insulin-like growth factor-2 levels in the blood. Elevated IGF-2 levels have been found in colorectal cancer patients, as this hormone promotes cell growth and survival, contributing to tumor development. Monitoring IGF-2 levels can provide valuable information about tumor activity and treatment response.

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Understanding Your Test Results

These specialized tests provide valuable information that complements traditional diagnostic methods. BRAF mutation testing helps guide personalized treatment decisions, while IGF-2 monitoring can offer insights into tumor behavior and treatment effectiveness. Your healthcare team will interpret these results in the context of your overall clinical picture.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with your oncologist or healthcare provider for proper diagnosis, treatment planning, and interpretation of test results.

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