Understanding Lab Tests for Coffee Allergy

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

Coffee allergy is an immune system reaction to proteins found in coffee beans. While true coffee allergies are relatively rare, they can cause symptoms ranging from mild skin reactions to respiratory issues and digestive problems. Specialized blood testing can help identify if your immune system is reacting to coffee.

Recommended Test

Food Specific IgG Allergy (Adult) Panel

This comprehensive panel measures IgG antibody levels specific to coffee (f221) and other foods. Elevated Coffee IgG antibodies indicate an immune response to coffee proteins, which can manifest as skin problems, respiratory issues, stomach cramps, and other delayed allergic symptoms. This test helps identify food sensitivities that may not be detected through traditional IgE allergy testing.

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How Coffee Allergies Are Detected

Coffee allergy diagnosis involves measuring specific antibodies in the blood that your immune system produces in response to coffee proteins. Unlike immediate allergic reactions that involve IgE antibodies, some coffee sensitivities involve IgG antibodies, which can cause delayed reactions that may occur hours or days after consumption.

Understanding Your Results

High levels of coffee-specific IgG antibodies suggest that your immune system recognizes coffee as a potential threat and is mounting a response. This can help explain symptoms that occur after coffee consumption and guide dietary modifications. It's important to work with a healthcare provider to interpret results and develop an appropriate management plan.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment. If you experience severe allergic reactions, seek immediate medical attention.

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