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Chronic Hepatitis A infection is a rare prolonged form of hepatitis A virus infection that persists for 6-9 months instead of resolving within weeks. It is caused by an extended immune response to the hepatitis A virus (HAV), resulting in persistent viral activity or relapsing illness. The Hepatitis A IgM Antibody test is the most important test for diagnosis because it detects the antibodies that remain elevated during this unusual chronic form of the infection.
Chronic hepatitis A infection is caused by an unusually prolonged immune response to the hepatitis A virus (HAV). While most people clear the acute hepatitis A infection within 2-3 months, some individuals experience persistent or relapsing viral activity that extends for 6-9 months. This extended course occurs when the body continues producing antibodies and inflammatory responses against the virus, preventing complete resolution of the infection.
The Hepatitis A IgM Antibody test is the most important test for chronic hepatitis A infection because it specifically detects IgM antibodies that indicate active or recent hepatitis A virus infection. In typical acute cases, these antibodies disappear within a few months, but in chronic hepatitis A, they persist for 6-9 months or longer. This test is essential for distinguishing chronic hepatitis A from other liver conditions and monitoring whether the prolonged infection has finally resolved. Your healthcare provider may also order liver function tests to assess ongoing liver inflammation.
You should get tested if you were previously diagnosed with hepatitis A but your symptoms have lasted longer than 3 months, if you experience recurring episodes of fatigue and jaundice after initial improvement, or if your liver enzymes remain elevated for an extended period. Testing is also important if you continue to have abdominal pain, dark urine, or persistent nausea months after your initial hepatitis A diagnosis. Early detection helps your healthcare provider monitor the unusual prolonged course and ensure proper management.
What this means
Your test came back negative, meaning no Hepatitis A IgM antibodies were detected in your blood. This indicates you do not currently have an active Hepatitis A infection, which is the expected and healthy result.
Recommended actions
Practice good hand hygiene, especially after using the bathroom and before handling food
Consider getting the Hepatitis A vaccine for long-term protection if not already vaccinated
Be cautious with food and water safety when traveling to areas where Hepatitis A is common
If symptoms persist or you suspect exposure, consult your doctor about retesting
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