Understanding Lab Tests for Chronic Fatigue Syndrome

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

Chronic Fatigue Syndrome (CFS) is a complex disorder characterized by extreme fatigue that cannot be explained by any underlying medical condition. There is no single blood test that can diagnose CFS; the diagnosis is typically made based on clinical symptoms and by ruling out other conditions. However, lab testing plays a fundamental role in identifying potential contributing factors that may exacerbate symptoms.

Top Recommended Test

Food Specific IgG Beet Root

Some individuals with chronic fatigue syndrome may have elevated levels of food-specific IgG antibodies, including those against beet root. Though the exact relationship is not well-understood, it is proposed that food intolerance may exacerbate symptoms of fatigue in these individuals by contributing to systemic inflammation.

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Why Blood Testing is Important for CFS Management

While blood tests cannot directly diagnose chronic fatigue syndrome, they are essential for assessing overall health, identifying potential triggers, and monitoring factors that may worsen fatigue symptoms. Food sensitivities, in particular, have been associated with increased inflammation and symptom exacerbation in some individuals with CFS.

Other Relevant Tests

Food Specific IgG Lima Bean

Food intolerance, as indicated by high levels of Food Specific IgG Lima Bean antibodies, can contribute to systemic inflammation and related fatigue. This inflammatory response can potentially exacerbate symptoms in individuals with Chronic Fatigue Syndrome, making identification of food sensitivities an important part of comprehensive management.

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Understanding Food Sensitivity Testing in CFS

Food-specific IgG testing measures immune reactions to specific foods. While the role of food sensitivities in CFS is still being researched, identifying and potentially eliminating trigger foods may help some individuals manage their symptoms more effectively as part of a comprehensive treatment approach.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment. CFS diagnosis requires comprehensive clinical evaluation by qualified medical professionals.

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