Understanding Lab Tests for Chronic Disease Anemia
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Chronic disease anemia, also known as anemia of inflammation, is a type of anemia that develops in patients with chronic illnesses such as infections, autoimmune disorders, kidney disease, or cancer. Unlike iron deficiency anemia, this condition occurs when the body's inflammatory response interferes with normal iron metabolism and red blood cell production.
Recommended Test
Soluble Transferrin Receptor
This test measures the levels of soluble transferrin receptor in the blood, which is a key marker for diagnosing chronic disease anemia. Elevated levels indicate that the body is attempting to increase iron uptake in response to inflammation, but the iron remains unavailable for hemoglobin synthesis due to the body's natural defense mechanism against pathogens during chronic illness.
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Diagnosing Chronic Disease Anemia
Diagnosing chronic disease anemia requires specific blood tests that can differentiate it from other types of anemia. The condition is characterized by the body's attempt to withhold iron from potential pathogens during chronic illness, which paradoxically leads to inadequate iron availability for healthy red blood cell production.
Understanding Your Results
High soluble transferrin receptor levels in the context of chronic illness suggest that your body is responding to inflammation by altering iron metabolism. This test helps healthcare providers distinguish chronic disease anemia from iron deficiency anemia, which is crucial for determining the most appropriate treatment approach.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment of chronic disease anemia.
