Understanding Lab Tests for Castleman Disease
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Castleman Disease is a rare disorder affecting the lymph nodes and related tissues. While diagnosis typically requires imaging studies and tissue biopsy, blood tests play a crucial role in monitoring disease activity, assessing complications, and guiding treatment decisions.
Recommended Test
Interleukin-6 (IL-6), Serum
This test measures IL-6 levels in the blood, which is particularly important for Castleman Disease patients. The condition is characterized by overproduction of IL-6, a key inflammatory protein. Elevated IL-6 levels can lead to systemic inflammation and dysfunction of multiple organ systems, making this test valuable for monitoring disease activity and treatment response.
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The Role of Blood Testing in Castleman Disease
Although there isn't a single blood test to diagnose Castleman Disease itself, laboratory testing is fundamental for understanding the body's inflammatory response and monitoring the systemic effects of this condition. Castleman Disease is characterized by overproduction of certain inflammatory proteins that can be measured through blood tests.
Understanding Your Results
Elevated IL-6 levels in Castleman Disease patients can help healthcare providers assess disease severity, monitor treatment effectiveness, and make informed decisions about ongoing care. Regular monitoring of these inflammatory markers is essential for managing the systemic effects of the condition.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment of Castleman Disease.
