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Cashew nut allergy is an immune system reaction to proteins found in cashews that can cause symptoms ranging from mild itching to severe anaphylaxis. It is caused by the immune system mistakenly identifying cashew proteins as harmful invaders and producing IgG and IgE antibodies to fight them. The Cashew Nut (f202) IgG test is the most important blood test for diagnosis because it measures specific antibodies that confirm your immune system has mounted a response to cashew proteins.
Cashew nut allergy is caused by your immune system misidentifying specific proteins in cashewsâprimarily Ana o 1, Ana o 2, and Ana o 3âas dangerous threats to your body. When you eat cashews or come into contact with cashew proteins, your immune system produces antibodies called immunoglobulin E (IgE) and immunoglobulin G (IgG) to attack these proteins. This immune response triggers the release of histamine and other chemicals that cause allergic symptoms, which can range from mild skin reactions to life-threatening anaphylaxis. The allergy can develop at any age, and even tiny amounts of cashew protein can trigger a reaction in sensitive individuals.
The Cashew Nut (f202) IgG test is the most important blood test for cashew nut allergy because it measures specific IgG antibodies your immune system produces in response to cashew proteins. This test provides clear laboratory evidence that your body has developed an immune sensitivity to cashews, distinguishing a true allergy from simple food intolerance. The blood test detects antibodies to cashew-specific proteins like Ana o 1, Ana o 2, and Ana o 3, giving you definitive confirmation of the allergy. Unlike symptom observation alone, this test provides objective data that helps you and your healthcare provider create an appropriate management plan, including strict avoidance strategies and emergency medication prescriptions if needed for severe reactions.
You should get tested if you experience symptoms like itching, tingling in your mouth, hives, skin rashes, or swelling of your lips, face, tongue, or throat after eating cashews or foods containing cashew ingredients. Testing is also important if you have digestive symptoms like nausea, stomach cramps, vomiting, or diarrhea following cashew consumption, or if you develop respiratory symptoms such as wheezing, nasal congestion, or difficulty breathing. If you have experienced anaphylaxisâa severe reaction with difficulty breathing, rapid pulse, dizziness, or loss of consciousnessâafter eating cashews, immediate testing is critical to confirm the allergy and obtain emergency medications like epinephrine auto-injectors.
What this means
Your IgG antibody levels to cashew nuts are elevated, suggesting your immune system is reacting to cashew proteins. This delayed immune response may be contributing to chronic symptoms like digestive discomfort, skin issues, or fatigue that occur hours or days after consuming cashews.
Recommended actions
Eliminate cashews and cashew-containing foods from your diet for 4-6 weeks
Keep a food diary to track symptoms and identify hidden sources of cashews
Replace cashews with alternative nuts like almonds or sunflower seeds if tolerated
Consider retesting in 3-6 months after dietary elimination to monitor antibody levels
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