Understanding Lab Tests for Cardiovascular Diseases

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

Cardiovascular diseases encompass a range of conditions affecting the heart and blood vessels, including coronary artery disease, heart attacks, stroke, and arrhythmias. While traditional diagnostic methods like ECGs and imaging are primary tools for diagnosis, specialized blood tests play a crucial role in identifying risk factors, monitoring treatment effectiveness, and detecting underlying causes that may contribute to cardiovascular disease development.

Top Recommended Test

TMAO (Trimethylamine N-Oxide)

This test measures TMAO levels, which are associated with increased cardiovascular disease risk. Elevated levels of TMAO can promote the formation of fatty plaques in the arteries through atherosclerosis, leading to increased risk of heart attack and stroke.

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$211

The Role of Specialized Blood Testing in Cardiovascular Health

Advanced blood tests can reveal important information about cardiovascular risk by detecting genetic predispositions, environmental toxin exposure, drug-related complications, and metabolic markers that traditional lipid panels might miss. These tests are fundamental for comprehensive cardiovascular risk assessment and personalized treatment planning.

Other Relevant Tests

Mercury Blood

This test measures mercury levels in blood, as studies have suggested a link between mercury exposure and increased risk of cardiovascular diseases including heart attacks and coronary heart disease. High levels of mercury in the blood may be a significant risk factor for these conditions.

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$103

Cocaine and Metabolites, Confirmation, Serum, Plasma, or Blood

This test detects cocaine and its metabolites, including benzoylecgonine, which can indicate chronic cocaine use. Excessive cocaine use can lead to serious cardiovascular diseases including coronary artery disease, arrhythmias, cardiomyopathy, and heart attack, making this test important for assessing drug-related cardiovascular risk.

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$443

AspirinWorks® 11-Dehydrothromboxane B2 (11-dhTXB2) with Creatinine

This test monitors the effectiveness of aspirin therapy by measuring 11-dhTXB2 levels. Increased levels can indicate that aspirin therapy is not effectively inhibiting thromboxane production, which can lead to an increased risk of blood clots and subsequently cardiovascular diseases such as heart attacks or strokes.

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$436

MTHFR Mutation(12) (QSC)

This genetic test identifies MTHFR gene mutations that can affect folate metabolism. Abnormal MTHFR function due to mutation can lead to elevated homocysteine levels, which is a recognized risk factor for various cardiovascular diseases, including heart disease, stroke, and peripheral vascular disease.

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$1,295

Understanding Your Cardiovascular Risk Profile

These specialized tests complement traditional cardiovascular assessments by providing insights into genetic predispositions, environmental exposures, medication effectiveness, and metabolic factors that can influence heart health. Results should be interpreted by healthcare professionals as part of a comprehensive cardiovascular risk evaluation.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment of cardiovascular conditions.

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