Understanding Lab Tests for Cardiac Amyloidosis

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

Cardiac amyloidosis is a rare disorder caused by deposits of abnormal proteins (amyloid) in heart tissue, making it difficult for the heart to function properly. While there is no single blood test that directly diagnoses cardiac amyloidosis, blood testing is fundamental for assessing heart function and monitoring the body's response to this condition.

Recommended Test

B-Type Natriuretic Peptide (BNP)

This test measures BNP levels in the blood, which become elevated when the heart is under stress or not pumping effectively. In patients with cardiac amyloidosis, BNP levels are often significantly increased due to the abnormal protein deposits interfering with normal heart function. This test is valuable for monitoring heart function and assessing the severity of cardiac involvement.

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The Role of Blood Testing in Cardiac Amyloidosis

Diagnosis of cardiac amyloidosis typically requires specialized imaging and tissue analysis. However, blood tests play a crucial supporting role by measuring biomarkers that indicate how well the heart is functioning and can help healthcare providers monitor disease progression and treatment response.

Understanding Your Results

Elevated BNP levels in the context of suspected cardiac amyloidosis can provide important information about heart function, but interpretation requires correlation with clinical symptoms, physical examination, and additional diagnostic tests. Your healthcare provider will use these results as part of a comprehensive evaluation.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.

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