Sample results
Autoimmune diseases occur when the immune system mistakenly attacks healthy tissues and organs in the body. They are caused by the production of autoantibodies that target the body's own cells, leading to conditions like rheumatoid arthritis, lupus, and Sjögren's syndrome. The IgG, IgA, Indirect Immunofluorescence test is the most important test for diagnosis because it detects the autoantibodies responsible for tissue damage.
Autoimmune diseases are caused by the immune system producing autoantibodies that mistakenly attack the body's own healthy tissues and organs. While the exact trigger varies by condition, genetic factors, environmental exposures, infections, and hormonal changes can all contribute to immune system dysfunction. In rheumatoid arthritis, autoantibodies attack joint tissues, while in lupus, they target multiple organs including the skin, kidneys, and heart.
The IgG, IgA, Indirect Immunofluorescence test is the most important test for autoimmune diseases because it detects autoantibodies commonly associated with lupus, Sjögren's syndrome, and rheumatoid arthritis. This test uses indirect immunofluorescence to identify antibodies attacking your own tissues, while elevated IgG levels indicate an overactive immune response. The Lymphocyte Subset Panel 4 (CD4:CD8 Ratio Profile) is also essential as it measures the ratio of CD4 to CD8 immune cells, which is often elevated in autoimmune conditions due to excess CD4 cells contributing to tissue damage.
You should get tested if you experience persistent joint pain and stiffness, unexplained fatigue that doesn't improve with rest, recurring fevers without infection, skin rashes that come and go, or swelling in multiple joints. Testing is especially important if you have a family history of autoimmune diseases or if your symptoms have lasted more than six weeks and affect your daily activities. Early detection through blood tests can help prevent serious organ damage and improve treatment outcomes.
What this means
Your test came back negative, meaning no anti-epithelial cell surface antibodies were detected in your blood. This is the expected and healthy result, suggesting no active autoimmune blistering disease affecting the connections between skin cells.
Recommended actions
Continue monitoring any skin symptoms and report new blistering to your doctor
Maintain good skin care practices and protect skin from excessive friction
If you develop unexplained blisters or sores, consider retesting
Follow up with your dermatologist if symptoms persist despite negative results
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Sample results
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