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Autoimmune diseases occur when the immune system mistakenly attacks healthy cells and tissues instead of foreign invaders. They are caused by immune system dysfunction where antibodies and immune proteins target the body's own organs and systems. The Liver Function Profile is the most important test for autoimmune disease screening because it measures globulin proteins that elevate when the immune system mounts an inflammatory response against its own tissues.
Autoimmune diseases are caused by immune system dysfunction where your body produces antibodies and immune cells that attack healthy tissues instead of foreign invaders like bacteria or viruses. The exact trigger varies by condition, but genetic factors, environmental exposures, infections, and hormonal changes can all contribute to the immune system losing its ability to distinguish between self and non-self. Common autoimmune conditions include rheumatoid arthritis, lupus, multiple sclerosis, type 1 diabetes, and celiac disease, each targeting different organs or body systems.
The Liver Function Profile is the most important test for autoimmune disease screening because it measures globulin proteins that elevate dramatically when your immune system attacks your own tissues. Elevated globulin levels serve as a red flag for autoimmune activity. The Protein Electrophoresis and Kappa/Lambda Light Chains test is essential for deeper evaluation, as it separates different blood proteins including gamma globulins that increase during autoimmune responses. Additionally, the Rubella Immune Status and Measles Antibody tests can reveal abnormally high antibody levels indicating immune system overactivity and dysfunction characteristic of autoimmune processes.
You should get tested if you experience persistent unexplained fatigue, joint pain or swelling, recurring fevers, skin rashes, digestive issues, or muscle weakness that lasts for weeks or months. Testing is especially important if you have a family history of autoimmune conditions, notice symptoms that come and go in flare-ups, or have multiple seemingly unrelated health issues affecting different body systems. Early detection through blood testing helps identify autoimmune activity before significant organ damage occurs and allows for prompt treatment to manage symptoms and prevent progression.
What this means
Your ALT level is slightly elevated above the optimal range, which may indicate mild liver inflammation or stress. This is commonly seen with fatty liver, alcohol use, certain medications, or metabolic conditions, and while not immediately alarming, it suggests your liver could benefit from some extra support.
Recommended actions
Reduce or eliminate alcohol consumption and limit processed foods
Incorporate regular exercise and work toward a healthy weight if needed
Increase intake of liver-supporting foods like leafy greens, beets, and cruciferous vegetables
Retest in 3-6 months to monitor improvement after lifestyle changes
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