Understanding Lab Tests for Antithrombin III Deficiency
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Antithrombin III deficiency is a hereditary blood clotting disorder that significantly increases the risk of developing abnormal blood clots (thrombosis). This condition occurs when the body doesn't produce enough antithrombin III protein, which normally helps prevent excessive blood clotting. Accurate diagnosis requires specific laboratory testing to measure antithrombin III levels in the blood.
Recommended Test
Antithrombin III Antigen
This test directly measures the amount of antithrombin III protein in the blood. In people with antithrombin III deficiency, the level of this protein is typically low, making this test the primary diagnostic tool for confirming the condition and assessing the severity of the deficiency.
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Diagnosing Antithrombin III Deficiency
Since antithrombin III deficiency often presents with recurrent blood clots or family history of clotting disorders, laboratory testing is essential for confirming the diagnosis. Early detection is crucial because individuals with this condition require specialized medical management to prevent life-threatening complications such as deep vein thrombosis or pulmonary embolism.
Understanding Your Results
Low antithrombin III antigen levels indicate a deficiency that requires medical attention and potentially lifelong anticoagulation therapy. Your healthcare provider will interpret your results in the context of your symptoms, family history, and overall health status to develop an appropriate treatment plan.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.
