Understanding Lab Tests for Androgen Deficiency

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

Androgen deficiency, also known as hypogonadism or low testosterone, is a condition where the body doesn't produce adequate levels of male hormones, primarily testosterone. This condition can affect men of all ages and requires specific blood testing for accurate diagnosis and monitoring.

Recommended Test

Testosterone, Free, Bioavailable and Total, LC/MS/MS

This comprehensive test measures all forms of testosterone in the blood using highly accurate LC/MS/MS technology. Low levels of bioavailable testosterone (the portion of testosterone available for the body to use) are a key indicator of androgen deficiency. This test provides the most complete picture of testosterone status, essential for confirming the diagnosis and determining appropriate treatment.

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Diagnosing Androgen Deficiency

Since symptoms of androgen deficiency such as fatigue, decreased libido, muscle weakness, and mood changes can overlap with many other conditions, definitive diagnosis relies on measuring testosterone levels in the blood. Comprehensive testosterone testing provides the most accurate assessment of androgen status.

Understanding Your Results

The test measures three important components: total testosterone (all testosterone in the blood), free testosterone (unbound and immediately available), and bioavailable testosterone (free plus loosely bound testosterone). Healthcare providers use these values together to make an accurate diagnosis and develop an appropriate treatment plan.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.

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