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Allergic urticaria, commonly known as hives, is a skin condition characterized by raised, itchy welts that appear suddenly on the skin. It is caused by an IgE-mediated immune response when the body encounters specific allergens such as foods, medications, insect stings, or environmental triggers like pollen and mold. The Allergen Specific IgE test is the most important test for diagnosis because it identifies which specific allergens trigger the immune system to release histamine and cause hives.
Allergic urticaria is caused by an IgE-mediated immune response when your body encounters specific allergens it recognizes as threats. Common triggers include foods like shellfish, nuts, and eggs, medications such as antibiotics and NSAIDs, insect stings from bees and wasps, and environmental allergens including pollen, mold, pet dander, and certain tree pollens like mulberry. When you are exposed to these allergens, your immune system releases histamine and other chemicals that cause blood vessels to leak fluid into the skin, creating the characteristic raised, itchy welts. The severity and duration of hives can vary depending on the allergen and your individual immune response.
The Allergen Specific IgE blood test is the most important test for allergic urticaria because it identifies the exact allergens triggering your immune system to produce hives. This test measures the levels of IgE antibodies in your blood that react to specific substances like foods, environmental allergens, medications, and insect venoms. For example, the Allergen Specific IgE Mulberry Red Tree test detects antibodies to mulberry tree pollen, which can cause seasonal hives in sensitive individuals. By pinpointing your specific triggers, these tests allow you to develop a targeted avoidance strategy and work with your healthcare provider on appropriate treatment plans, including antihistamines or immunotherapy when needed.
You should get tested if you experience recurrent episodes of raised, itchy welts on your skin that appear suddenly and seem to be triggered by specific exposures to foods, outdoor activities, medications, or seasonal changes. Testing is particularly important if your hives persist for more than six weeks, interfere with your daily activities or sleep, or if you have experienced severe reactions like swelling of the face or throat. You should also consider testing if over-the-counter antihistamines are not effectively controlling your symptoms, or if you want to identify specific triggers to avoid future reactions and improve your quality of life.
What this means
Your IgE antibody level to mulberry red tree pollen is elevated, indicating you have a moderate allergic sensitivity to this tree. This explains symptoms like sneezing, itchy eyes, and congestion you may experience during mulberry pollination season, typically in spring and early summer.
Recommended actions
Monitor local pollen counts and limit outdoor activities during peak times
Keep windows closed during allergy season and use HEPA air filters at home
Rinse nasal passages with saline solution after outdoor exposure
Consider over-the-counter antihistamines or consult an allergist for treatment options
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