Alcoholic Hepatitis Blood Test

What is Alcoholic Hepatitis?

Alcoholic hepatitis is a serious liver condition characterized by inflammation and damage to liver tissue. It is caused by excessive and prolonged alcohol consumption that overwhelms the liver's ability to process alcohol, leading to toxic byproduct accumulation and inflammatory responses. The Alkaline Phosphatase Isoenzymes test is the most important test for diagnosis because it measures specific liver enzymes that become elevated when the liver is inflamed or damaged.

RECOMMENDED TEST Alkaline phosphatase isoenzymes
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What causes alcoholic hepatitis?

Alcoholic hepatitis is caused by excessive and prolonged alcohol consumption that damages liver cells. When you drink alcohol, your liver breaks it down into toxic substances like acetaldehyde, which trigger inflammation and kill liver cells. Heavy drinking over many years overwhelms the liver's ability to repair itself, leading to progressive inflammation and scarring. The risk increases significantly with drinking more than 3-4 drinks daily for men or 2-3 drinks daily for women over several years.

What is the best test for alcoholic hepatitis?

The Alkaline Phosphatase Isoenzymes test is the most important test for alcoholic hepatitis because it specifically identifies elevated liver enzymes that indicate active liver inflammation and damage. This test measures different forms of alkaline phosphatase enzymes, and the liver-specific isoenzymes become markedly elevated when the liver is inflamed from alcohol consumption. Your healthcare provider may also order additional tests like AST, ALT, GGT, bilirubin, and complete blood counts to assess the full extent of liver damage and rule out other causes of liver disease.

When should I get tested for alcoholic hepatitis?

You should get tested if you have a history of heavy alcohol use and develop symptoms like yellowing of the skin or eyes (jaundice), abdominal pain especially in the upper right side, nausea and vomiting, fever, or unexplained fatigue and weakness. Testing is also important if you notice swelling in your abdomen or legs, loss of appetite, or if you've been told you have elevated liver enzymes in the past. Early detection through blood testing can help prevent progression to more severe liver damage like cirrhosis.

What are the symptoms of alcoholic hepatitis?
Symptoms of alcoholic hepatitis include jaundice (yellowing of the skin and eyes), abdominal pain and tenderness particularly in the upper right side, nausea and vomiting, fever, and extreme fatigue. You might also experience loss of appetite, weight loss, swelling in the abdomen or legs, confusion or mental changes, and easy bruising or bleeding. Some people with mild alcoholic hepatitis may have no symptoms at all, while others with severe cases can develop life-threatening complications requiring immediate medical attention.
Who is at risk for alcoholic hepatitis?
People who consume large amounts of alcohol regularly are at highest risk for alcoholic hepatitis, particularly those drinking more than 3-4 drinks daily for men or 2-3 drinks daily for women over many years. Women are more susceptible than men to alcohol-related liver damage even at lower consumption levels. Other risk factors include obesity, malnutrition, genetic factors that affect alcohol metabolism, hepatitis C infection, and continuing to drink alcohol despite having existing liver disease. Binge drinking patterns also significantly increase risk.
What happens if alcoholic hepatitis is left untreated?
Untreated alcoholic hepatitis can progress to life-threatening complications including cirrhosis (permanent liver scarring), liver failure, bleeding from enlarged veins in the esophagus, kidney failure, and liver cancer. The inflamed liver loses its ability to perform essential functions like filtering toxins, producing proteins needed for blood clotting, and processing nutrients. Severe alcoholic hepatitis has a mortality rate of 30-50% within 30 days without treatment. Complete abstinence from alcohol and early medical intervention are critical to prevent these potentially fatal outcomes.
Can alcoholic hepatitis be diagnosed with a blood test?
Yes, alcoholic hepatitis can be diagnosed with blood tests that measure liver enzymes and function markers. The Alkaline Phosphatase Isoenzymes test specifically identifies liver inflammation, while other blood tests like AST, ALT, GGT, and bilirubin levels help confirm the diagnosis and assess severity. Blood tests also evaluate liver function by measuring albumin, prothrombin time, and complete blood counts. While blood tests are essential diagnostic tools, your doctor will also consider your medical history, alcohol consumption patterns, physical examination findings, and sometimes imaging studies or liver biopsy for a complete assessment.
How is alcoholic hepatitis treated?
Treatment for alcoholic hepatitis begins with complete and permanent abstinence from alcohol, which is essential for recovery and preventing further liver damage. Your doctor may prescribe corticosteroids like prednisolone to reduce liver inflammation in severe cases, along with nutritional support including vitamin supplements, protein, and calories to address malnutrition. Treatment also includes managing complications like fluid retention, infections, and bleeding problems. In severe cases that don't respond to medical treatment, liver transplantation may be considered, but this requires documented sobriety. Support programs and counseling are crucial for maintaining alcohol abstinence.
How can I prevent alcoholic hepatitis?
You can prevent alcoholic hepatitis by limiting alcohol consumption to moderate levels or avoiding alcohol entirely, especially if you have risk factors for liver disease. Moderate drinking means no more than one drink per day for women and two drinks per day for men. Maintain a healthy weight through balanced nutrition and regular exercise, as obesity increases liver disease risk. Get vaccinated against hepatitis A and B to protect your liver from additional damage. If you have trouble controlling your drinking, seek help from addiction specialists or support groups before liver damage occurs.
What can I do at home for alcoholic hepatitis?
At home, the most critical step is to stop drinking alcohol completely and permanently, as continued drinking will worsen liver damage and can be fatal. Focus on eating a nutritious diet rich in fruits, vegetables, lean proteins, and whole grains while limiting salt if you have fluid retention. Stay well-hydrated with water and avoid medications that can harm the liver, including acetaminophen and unnecessary supplements. Get adequate rest and avoid exposure to other liver toxins like certain cleaning chemicals. However, home management should complement, not replace, professional medical treatment, so maintain regular follow-up with your healthcare provider to monitor your liver function.
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If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
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Liver Isoenzymes 65 U/L
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65 U/L

What this means

Your liver isoenzyme levels are elevated above the optimal range, which suggests increased liver activity or possible liver stress. This could be related to liver inflammation, bile duct issues, fatty liver, or certain medications. While not necessarily alarming, it warrants attention and may benefit from lifestyle modifications or further evaluation.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.

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* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.

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Alkaline phosphatase isoenzymes
What's included
Fast & easy, results by email & SMS
No need to visit a doctor
Private & confidential
No insurance needed
Results explained
No extra fees paid at the lab

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