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Acute kidney failure, also known as acute kidney injury (AKI), is a sudden loss of kidney function that occurs within hours or days. It is caused by severe dehydration, traumatic injury, toxic medications, infections, or blockages that prevent the kidneys from filtering waste products from the blood. The Urea Nitrogen (BUN) test is the most important test for diagnosis because it detects rapid accumulation of waste products in the bloodstream.
Acute kidney failure is caused by conditions that suddenly damage the kidneys or reduce blood flow to them, preventing proper waste filtration. Common causes include severe dehydration from vomiting or diarrhea, traumatic injuries with significant blood loss, sepsis and serious infections, toxic medications like NSAIDs or certain antibiotics, and urinary tract blockages from kidney stones or enlarged prostate. Other triggers include heart failure, liver failure, severe burns, and allergic reactions that cause blood pressure to drop suddenly. The kidneys lose their ability to remove waste products and balance electrolytes within hours or days, making this a medical emergency requiring immediate treatment.
The Urea Nitrogen (BUN) test is the most important test for acute kidney failure because it measures the amount of urea nitrogen waste product in your blood that healthy kidneys normally filter out. When your kidneys suddenly stop working properly, BUN levels rise rapidly, providing clear evidence of kidney dysfunction. The creatinine blood test is equally essential and is often ordered alongside BUN, as creatinine is another waste product that accumulates when kidney filtration fails. Together, these tests create a BUN-to-creatinine ratio that helps doctors determine the severity and type of kidney failure. Additional tests may include electrolyte panels to check potassium and sodium levels, and urinalysis to examine protein and blood in the urine.
You should get tested if you suddenly produce very little urine or stop urinating altogether, experience severe swelling in your legs, ankles, or feet, feel extremely fatigued or confused, have persistent nausea and vomiting, or notice shortness of breath. Get immediate testing if you have chest pain or pressure, as fluid can build up around the heart. Anyone hospitalized for serious injury, major surgery, sepsis, or severe dehydration should be monitored with regular kidney function tests. If you take medications known to affect the kidneys, such as NSAIDs, certain antibiotics, or blood pressure medications, and develop any of these symptoms, testing is critical for early detection.
What this means
Your BUN level is slightly elevated, which may indicate mild dehydration or that your kidneys are working harder than ideal to filter waste. This could also be related to a high-protein diet or certain medications. While not necessarily concerning on its own, it's worth monitoring and addressing potential causes.
Recommended actions
Increase your daily water intake to stay well-hydrated throughout the day
Reduce sodium intake by limiting processed foods and salty snacks
Consider moderating protein intake if you consume large amounts daily
Retest in 4-6 weeks after making hydration and dietary adjustments
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