Understanding Lab Tests for Active Tuberculosis

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

Active tuberculosis (TB) is a serious infectious disease caused by Mycobacterium tuberculosis bacteria that primarily affects the lungs but can also impact other parts of the body. While TB diagnosis typically involves multiple approaches including clinical evaluation and imaging, blood tests play a crucial role in detecting the infection and supporting the diagnostic process.

Recommended Test

QuantiFERON®-TB Gold Plus

This advanced blood test detects Mycobacterium tuberculosis infection by measuring the immune system's response to specific TB antigens. The test works by analyzing how white blood cells react when exposed to TB proteins, providing valuable information about TB infection status. A positive result may indicate active tuberculosis and warrants immediate medical attention and further evaluation.

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The Role of Blood Testing in TB Diagnosis

Blood tests for tuberculosis work by detecting the immune system's response to TB bacteria. These tests are fundamental for identifying TB infection, especially when used alongside other diagnostic methods. A positive blood test result can indicate the presence of TB bacteria and help healthcare providers determine the need for further evaluation and treatment.

Understanding Your Test Results

The QuantiFERON-TB Gold Plus test provides reliable results that help distinguish between TB infection and other conditions. However, it's important to understand that blood test results should always be interpreted by a healthcare professional in conjunction with clinical symptoms, medical history, and other diagnostic findings to ensure accurate diagnosis and appropriate treatment planning.

Important Considerations

Active tuberculosis is a serious medical condition that requires immediate professional medical care. The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for proper diagnosis, treatment, and monitoring of tuberculosis.

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