Sample results
Active tuberculosis is a contagious bacterial infection that primarily attacks the lungs and can spread throughout the body. It is caused by Mycobacterium tuberculosis bacteria transmitted through airborne droplets when infected individuals cough or sneeze. The QuantiFERON-TB Gold Plus blood test is the most important test for detecting tuberculosis infection by measuring immune system response to TB antigens.
Active tuberculosis is caused by Mycobacterium tuberculosis bacteria that spread through the air when an infected person coughs, sneezes, speaks, or sings. When you breathe in these bacteria, they settle in your lungs and begin to multiply, eventually spreading to other parts of your body through your bloodstream. People with weakened immune systems are especially vulnerable to developing active TB after exposure to the bacteria.
The QuantiFERON-TB Gold Plus is the most important blood test for active tuberculosis because it detects Mycobacterium tuberculosis infection by measuring your immune system's specific response to TB proteins. This test analyzes how your white blood cells react when exposed to TB antigens, providing reliable results that help identify TB infection. Unlike older skin tests, the blood test requires only one visit, produces results within 24 hours, and is not affected by previous BCG vaccinations. A positive result indicates TB infection and requires immediate medical follow-up with additional tests like chest X-rays and sputum cultures to confirm active disease.
You should get tested if you experience persistent cough lasting more than three weeks, unexplained weight loss, night sweats, fever, or coughing up blood. Testing is also important if you have been in close contact with someone diagnosed with TB, work in healthcare settings, have traveled to countries where TB is common, or have conditions that weaken your immune system like HIV or diabetes. Early detection is critical because active TB can spread to others and cause serious complications if left untreated.
What this means
Your test came back negative, meaning no TB infection was detected. This is the expected and healthy result, indicating your immune system has not been exposed to tuberculosis bacteria or that any previous exposure has been cleared.
Recommended actions
Continue practicing infection prevention if you work in healthcare or high-risk settings
Consider annual retesting if you work in environments with TB exposure
Seek testing promptly if you have close contact with someone diagnosed with TB
Maintain good overall health with adequate nutrition and sleep to support immune function
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