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Protein, Total, Serum Test
This test is used to
evaluate nutritional status, investigate edema and as part of an investigation
into various liver, kidney and gastrointestinal diseases. Very low total protein
(<4 g/dL) and low albumin cause edema (eg, the nephrotic syndromes).
high total protein: dehydration; some cases of chronic liver
disease, including chronic active hepatitis and cirrhosis; neoplasms, especially
myeloma; macroglobulinemia of Waldenström; tropical diseases (eg, kala-azar,
leprosy, and others); granulomatous diseases, such as sarcoidosis; diseases
in which total protein is sometimes high include collagen disease (eg, lupus
erythematosus (SLE), and other instances of chronic infection/inflammation).
Causes of low total protein:
pregnancy; intravenous fluids; cirrhosis or other liver disease,
including chronic alcoholism; prolonged immobilization; heart failure; nephrotic
syndromes; glomerulonephritis; neoplasia; protein losing enteropathies; Crohn
disease and chronic ulcerative colitis; starvation, malabsorption or malnutrition;
hyperthyroidism; burns; severe skin disease; and other chronic diseases.
A significant deviation from the
normal range may require further evaluation by your physician.
Private MD Lab Services
offers the following test for protein, total, serum: