Description: Gamma Glutamyl Transpeptidase (GGT) is a biliary enzyme. This test is typically ordered when liver disease is suspected. The GGT test will help diagnose injury to the liver and bile duct.
Elevated GGT is found in all forms of liver disease. Measurement of GGT is used in the diagnosis and treatment of alcoholic cirrhosis, as well as primary and secondary liver tumors. It is more sensitive than alkaline phosphatase, the transaminases, and leucine aminopeptidase in detecting obstructive jaundice, cholangitis, and cholecystitis. Normal levels of GGT are seen in skeletal diseases; thus, GGT in serum can be used to ascertain whether a disease, suggested by elevated alkaline phosphatase, is skeletal or hepatobiliary.
Significant deviations from the normal range may require further evaluation by your physician.