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arsenic_exposure_urine.php
Arsenic Exposure Profile, Urine
This test profile is used to monitor
chronic exposure to arsenic.
Arsenic poisoning of a chronic
nature is often evidenced by cardiovascular abnormalities and neurological
disorders. Acute exposures to high concentrations of arsenic may be evidenced
by the following signs and symptoms:
- Gastrointestinal: Severe abdominal pain, nausea and vomiting, bloody or
rice-water diarrhea
- Cardiovascular and respiratory: Hypotension, shock, ventricular arrhythmia,
congestive heart failure, pulmonary edema
- Neurologic: Lightheadedness, headache, weakness, lethargy, delirium, encephalopathy,
convulsions, coma, sensorimotor peripheral neuropathy
- Hepatic and renal: Elevated liver enzymes, hematuria, oliguria, proteinuria,
acute tubular necrosis, renal cortical necrosis
- Hematologic: Anemia, leukopenia, thrombocytopenia, disseminated intravascular
coagulation
- Other: Rhabdomyolysis, garlic odor on breath, delayed appearance of Mees
lines
Generally, inorganic arsenic is associated
with industry and has a higher rate of toxicity than does the organic arsenic
that is usually associated with dietary intake. Urine offers the better medium
for analyzing a chronic or prolonged arsenic exposure. Possible dietary or
domestic sources of arsenic should be considered if urine concentrations remain
above the norm.
Arsenic compounds in organic forms
have numerous commercial applications (eg, arsenical pesticides, pharmaceuticals,
ceramic glass industry, and metallurgy). Arsine gas may also be emitted as
a byproduct of certain industries, such as metallurgy. Organic forms of arsenic
are typically encountered from dietary intake. BEI® are reference values intended
as guidelines for evaluation of occupational exposure. BEI® represent biological
levels of chemicals that correspond to workers with inhalation exposure equivalent
to the threshold limit value (TLV®) of the chemicals. TLV®s refer to the airborne
concentrations of substances and represent conditions under which it is believed
that nearly all workers may be repeatedly exposed, day after day, without
adverse health effects.
A significant deviation from the
normal range may require further evaluation by your physician.
Private MD Lab Services
offers the following tests for arsenic exposure profile, urine:
The Arsenic
Exposure Profile, Urine contains the following tests:
arsenic (total), urine
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arsenic (inorganic), urine |
creatinine, urine |
arsenic (inorganic):creatinine ratio |
arsenic (total), urine (24-hour) |
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