Thrombin Mixing Study Test

This test is used in the diagnosis of fibrinogen deficiency, both congenital and acquired and to identify heparin contamination of samples.

Thrombin time will be extended when functional fibrinogen levels are <100 mg/dL. This can occur due to congenital conditions including afibrinogenemia (complete lack of fibrinogen), hypofibrinogenemia, and in dysfibrinogenemia, a condition characterized by the presence of dysfunctional fibrinogen. Acquired conditions can lead to diminished fibrinogen levels and extended thrombin times include liver disease, renal disease, disseminated intravascular coagulation (DIC), amyloidosis, malignancy, and thrombolytic therapy. Thrombin inhibitors including heparin, argatroban, and hirudin will cause an extended thrombin time.

A significant deviation from the normal range may require further evaluation by your physician.

Private MD Lab Services offers the following test for Thrombin Mixing Study:

Thrombin Mixing Study Test  $98.99	Add To Cart

The Thrombin Mixing Study contains the following tests:

thrombin time	reflex to thrombin time 1:1 mix
thrombin neutralization