Lupus Anticoagulant with Reflex Test

This test is used for the qualitative detection of lupus anticoagulants in plasma.

Lupus anticoagulants are nonspecific antibodies that extend the clotting time of phospholipid-dependent clotting assays such as the aPTT. Unlike specific factor antibodies, LA are usually associated with venous thrombosis, pulmonary embolism, arterial thrombosis, and recurrent fetal loss. LA do not specifically inhibit individual coagulation factors; rather they neutralize anionic phospholipid-protein complexes that are involved in the coagulation process. Prolongation of clot-based assays is highly dependent on the sensitivity of the reagent employed. Reagents with reduced amounts of phospholipid, such as the aPTT-LA and dilute Russell viper venom time (dRVVT), have enhanced sensitivity for LA. Due to the heterogeneity of LA antibodies, no single assays will identify all cases. The International Society on Thrombosis and Haemostasis (ISTH) has established criteria for the diagnosis of lupus anticoagulants.

A significant deviation from the normal range may require further evaluation by your physician.

Private MD Lab Services offers the following test for Lupus Anticoagulant with Reflex:

Lupus Anticoagulant with Reflex Test  $299.99	Add To Cart