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Free Kappa & Lambda Light Chains, Quantitative, SerumElevated serum levels of monoclonal free light chains (FLC) are associated with malignant plasma cell proliferation (eg, multiple myeloma), primary amyloidosis, and light chain deposition disease. Raised serum levels of polyclonal FLC may be associated with autoimmune diseases such as systemic lupus erythematosus. The appearance of higher levels of FLC in urine may be indicative of kidney disease or malignant lymphoproliferative disease such as multiple myeloma. The monoclonal urinary FLC associated with lymphoid malignancy is called a Bence Jones protein. Private MD Lab Services offers the following serum test to detect and measure free light chains:
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