Human Herpes Virus-6, IgG Test
This test
assists in the diagnosis of past infection/exposure to roseola
infantum in children; may be useful in diagnosis of chronic
fatigue syndrome in adults.
Human herpesvirus 6 (HHV-6) has
recently been identified as the agent associated with both pediatric and adult
infections. Most children have been infected by age three years of age. The
acute infection in children is characterized clinically by an acute febrile
illness, irritability, inflammation of tympanic membranes, and (uncommonly)
a rash characteristic of roseola. When acute and convalescent (four to six
weeks later) serum samples are compared, a fourfold rise in HHV-6 IgG titer
is typical.
In adults, HHV-6 has been associated
with chronic fatigue and spontaneously resolving fever resembling a mononucleosis-like
illness. During the acute episode an elevated IgM HHV-6 is useful. An increase
in IgG HHV-6 between acute and convalescent serum sample is consistent with
a recent HHV-6 infection.
Private MD
Lab Services offer the following test to help diagnose human
herpes virus-6 infection:
