Call us: 1.877.283.7882 | Monday–Friday: 8:00 AM–4:30 PM ET

Private MD News - Diabetes

Home | News | Diabetes

View Articles by Date

Year: 2013 2012 2011 2010 2009

Month: JAN FEB MAR APR MAY JUN JUL AUG SEP OCT NOV DEC

Enzyme may be linked to angina in type 2 diabetes patients
Date: 2012-11-28 19:05:23

Researchers at the Karolinska Institutet in Sweden have found that an enzyme known as arginase may contribute to the development of angina in patients with type 2 diabetes.

According to the National Institutes of Health (NIH), angina is a cardiovascular condition in which pain in the chest, shoulders, arms, neck and back occurs due to a deficiency of oxygen and blood flow to the heart.

During the study the scientists looked at patients with angina and type 2 diabetes, which can be detected with a blood test. They found that the arginase enzymes inhibit nitric oxide molecules from forming, and according to study investigator John Pernow, M.D., Ph.D., F.E.S.C, plays a crucial role in dilating vessel walls and preventing plaque buildup.

"The fact that we could demonstrate the presence of arginase in several types of cells in the vessel walls gives us an entirely new explanatory model for the development of complications in these patients," said Pernow.

When the subjects were given a medication that suppressed the enzyme, blood flow improved. The researchers also found that the enzyme-inhibiting drug did not help patients with angina who did not have type 2 diabetes and did not affect subjects who did not have any of the conditions.

The Karolinska Institutet researchers are planning a follow-up study, which will test the effects of the enzyme-inhibitor drug on a larger group of subjects.

Angina facts... Full Story

Subscribe to Private MD Health News RSS Feed: Subscribe

News Categories:

Advanced Lipid Treatment I   Allergy Testing   Anemia and RBC disorders   Autoimmune Diseases   Bariatric Lab Testing   Blood and Blood Diseases   Breast   Cancer Detection and Tumor Markers   Celiac Disease Testing   Chlamydia   Coagulation and blood clotting disorders   Colon   Diabetes   DNA, Paternity and Genetic testing   Drug Screening   Environmental Toxin Testing   Female Specific Tests   Gastrointestinal Diseases   General Health   General Wellness   Heart Health and Cholesterol   Herpes   HIV   HIV monitoring/Treatment/Testing/Post Diagnos   Hormones and Metabolism   Infectious Diseases   Infertility Testing-Male   Infertitlity Hormone Testing   Kidney Diseases   Leukemia and WBC disorders   Liver   Liver Diseases   Lyme Disease   Male Specific Tests   Menopause/Peri-Menopausal Diagnosis   Musculoskeletal Diseases   Organ Specific Testing   Ovarian   Prostate   Sexually Transmitted Diseases   Thyroid Diseases   Transgender Hormone Testing-female to male   Transgender Hormone Testing-Male to Female   Vitamin D Deficiency-Diagnosis and Treatment   

 

Visit the Health News Archive: Click Here

Questions about online blood testing or how to order a lab test? Click here to get started or call us toll-free at 1.877.283.7882. Our certified professionals are ready to assist you.

Back to top